WebJiang Peiyong Dennis Lo A new assay for cell-free DNA fragmentation improves prediction of gene expression in liquid biopsies. View Single-molecule sequencing reveals a large … WebMay 27, 2024 · These features are promising to be applied in various scenarios such as prenatal diagnosis, early cancer detection and therapy response monitoring ( Kilgour et al., 2024; Oliveira et al., 2024 ). However, there still lacks an integrative and systematic tool for cfDNA HTS data processing and analysis.

cfDNApipe: a comprehensive quality control and analysis pipeline …

Web2 days ago · Targeting oncofusion proteins is an attractive approach for cancer treatment. First, fusion proteins are specifically expressed in cancer cells rather than in normal cells. Accordingly, the specific targeting of fusion proteins potentially offers limited toxicity. Furthermore, fusion proteins may be the sole driver of some cancers, making them ... WebApr 14, 2024 · Introduction. Gastric cancer remains a major contributor to global cancer incidence and mortality, which is responsible for over 700,000 deaths each year (Sung et al., 2024).More than 95% of gastric cancer cases are adenocarcinomas, usually classified according to anatomical location and histological type (Ajani et al., 2024).Among … chinese cooking classes online

Unveiling DNA damage repair-based molecular subtypes, tumor ...

WebFeb 3, 2024 · During the last decade, immunotherapy has radically changed perspectives on anti-tumor treatments. However, solid tumor treatment by immunotherapy has not met expectations. Indeed, poor clinical response to treatment has highlighted the need to understand and avoid immunotherapy resistance. Cholangiocarcinoma (CCA) is the … WebDec 3, 2024 · Sarah T. K. Sin, Peiyong Jiang, Jiaen Deng, +6, ... Also, Kumar et al. reported that for lung cancer and ovarian cancer patients, eccDNA detected from presurgery plasma were of larger sizes than those from postsurgery plasma samples. Thus, we hypothesize that the differences in sizes and 10-bp periodicity sharpness between maternal and fetal ... WebDec 21, 2024 · Jiang et al. found that plasma DNA molecules contained a significantly higher level of jaggedness than the sonicated DNA molecules, with 88% of plasma DNA molecules carrying jagged ends. Interestingly, the property of plasma DNA jagged ends appears to be associated with tissue of origin. chinese cooking courses