Phorbol myristoyl acetate
WebPhorbol 12-myristate 13-acetate, 97%, Thermo Scientific Chemicals. Catalog number: 356150050. 245.00 / Each. Add to cart. WebPhorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. Cell Signal. 17(3):299-310. 3. Fürstenberger G. et al., 1981. Skin tumor promotion by phorbol esters is a two-stage process. PNAS. 78(12):7722-6. TECHNICAL SUPPORT
Phorbol myristoyl acetate
Did you know?
Webdisulfonic acid, phorbol myristoyl acetate (PMA), desferrioxamine, and all other reagents were from Sigma. 55FeCl 3 (9.1 mM, 20 mCi/mg) was from PerkinElmer Life Sciences. A 55Fe-NTA solution was prepared by incubating 55FeCl 3 (9.1 mM) and NTA (45.5 mM) for 1 h. The resulting 55Fe-NTA solution was mixed at a 1:9 molar ratio with unlabeled WebZoom. Phorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS.
WebMixed lineage kinase 3 inhibits phorbol myristoyl acetate-induced DNA synthesis but not osteopontin expression in rat mesangial cells Authors Narayanan Parameswaran 1 , … WebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a specific activator of Protein Kinase C (PKC) and hence activates nuclear factor-kappa B (NF-κB). NF-κB is a transcription factor that regulates numerous physiological functions and is involved in the pathogenesis of various diseases.
WebJun 30, 1988 · It is concluded that phorbol esters stereospecifically enhance the Ca 2+ -sensitivity of glutamate release, but that higher concentrations may be required than for protein kinase C translocation in the same preparation. Instead the enhancement may be related to the rapid inactivation of protein kinase C which occurs with phorbol esters. … WebFeb 24, 2014 · Luteolin (LU) is a potent natural mast cell stabilizer. However, a direct correlation between LU and these common metabolic diseases is not established. Methods and results Male C57BL/6 mice were fed low-fat diet, high-fat diet (HFD), HFD with 0.002 and 0.01% LU for 12 wk, respectively.
WebSAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 24-Dec-2024 Revision Number 4 1. Identification Product Name Phorbol 12-myristate 13-acetate Cat No. : BP685, BP685-1, BP685-10, BP685-5 CAS No 16561-29-8 Synonyms PMA Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product use. …
WebPhorbol myristoyl acetate (PMA) and phosphatase inhibitor cocktail were from Sigma-Aldrich (St. Louis, MO, USA). The following Western blot antibodies were used: anti-PDHE1 and anti-VDAC (Invitrogen, Carlsbad, CA, USA); anti-PKC by measuring the increase in absorbance at 340 nm of a reactionand anti-Tim23 (BD Biosciences, San Jose, CA, church of christ chattanooga tnchurch of christ chicago ilWebIn order to test the biological relevance and potential interaction of MLK 3 with protein kinase C-mediated signaling pathways, human MLK 3 was stably expressed in rat glomerular mesangial cells using a retroviral vector (LXSN) and the effects of phorbol myristoyl acetate (PMA) on DNA synthesis and osteopontin mRNA expression were examined. dewalt hacksaw cordlessWeb1我会变成一只藏在你胸口的蝴蝶，飞舞在你深藏却视而不见的地方，听外面的世界兵荒马乱。而我躲在你的心房，像大海沉入 ... dewalt hacksaw instructionsWebJun 3, 2024 · I want to use the PMA solution to stimulate THP-1 (1x106 cells/ml), so I will choose one tube of PMA and dilute it by adding 990uL PBS so that the concentration of PMA reach to 10ug/ml. 25uL PMA ... church of christ christian worker magazineWebGeneral description. Phorbol 12-myristate 13-acetate is a phorbol ester. It works as a tumor promoter and is involved in gene transcription, cell growth, differentiation, programmed … church of christ church directoryWebPhorbol 12-myristate 13-acetate Synonym (s): Phorbol-12-myristate-13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, PMA, TPA Empirical Formula (Hill Notation): C36H56O8 CAS No.: 16561-29-8 Molecular Weight: 616.83 Beilstein No.: 2407201 church of christ christian singles