Staurosporine camptothecin and etoposide
WebStaurosporine Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases.; ... Etoposide. synthetic, 95.0-105.0%, powder. View Price and Availability. Sigma-Aldrich. C9911 (S)-(+)-Camptothecin. ≥90% (HPLC), powder. View Price and Availability. Properties. Quality Level ... WebStaurosporine (ab120056) 1 µM (1 mM stock prepared in DMSO) Etoposide (ab120247) 1–10 µM (1 mM stock prepared in DMSO) Camptothecin (ab120115) 2–10 µM (1 mM … Apoptosis is a mechanism of programmed cell death that occurs in multicellular …
Staurosporine camptothecin and etoposide
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WebMar 23, 2024 · API5-depleted cells were sensitized to PFT but not to TNF-α/CHX, staurosporine, camptothecin, etoposide, cisplatin and brefeldin A (Fig 3 A and B). To avoid any cell type-specific phenotypes, we performed similar experiments in NCI-H1650 lung carcinoma cell lines. WebDescribed is a method of apoptosis induction as a positive control for cell death assays, specifically a method for inducing apoptosis using camptothecin. Camptothecin …
WebJan 4, 2005 · Camptothecin- and etoposide-induced apoptosis in human leukemia cells is independent of cell death receptor-3 and -4 aggregation but accelerates tumor necrosis factor–related apoptosis-inducing ligand–mediated cell death Molecular Cancer Therapeutics American Association for Cancer Research Article ARTICLE January 04 … WebApr 10, 2001 · Staurosporine induces apoptosis in the Jurkat subclone JM319 resistant to anticancer drug- and CD95-induced apoptosis. Dose response with anti-CD95 ( a ), etoposide ( b ), daunorubicin ( c) and...
Webcamptothecin or staurosporine with concentrations ranging . media also contained reagents from the Kinetic Apoptosis Kit (ab129817), donated by Abcam (Cambridge, MA). The … WebMar 31, 2024 · Ability of pharmacological quiescence to protect against chemotherapy-induced γ-H2AX formation and apoptosis. The tHDF cells were treated with varying concentrations of PD0332991 (PD) before treatment with 100 μM carboplatin, 1 μM doxorubicin, 5 μM etoposide, 156 nM camptothecin, 250 nM paclitaxel, or 1.5 nM …
WebDescribed is a method of apoptosis induction as a positive control for cell death assays, specifically a method for inducing apoptosis using camptothecin. Camptothecin apoptosis induction protocol Materials A cell line or primary cells susceptible to apoptosis induction. RPMI-1640 medium supplemented with 10% FBS
new chic en argentinaWebKR102512597B1 KR1020247033500A KR20247033500A KR102512597B1 KR 102512597 B1 KR102512597 B1 KR 102512597B1 KR 1020247033500 A KR1020247033500 A KR 1020247033500A KR 20247033500 A KR20247033500 A KR 20247033500A KR 102512597 B1 KR102512597 B1 KR 102512597B1 Authority KR South Korea Prior art keywords cmet … internet back wedding photographerWebround-bottom, 96-well plate. Staurosporine, camptothecin, cycloheximide, or etoposide were added to individual wells to various final concentrations ranging from 100 µM to 2 nM (each in triplicate) in a final volume of 150 µL per well (Figure 1). Cells were incubated with the various drug concentrations at 37°C and in 5% CO 2 for 4 hours. internet bad creditWebMar 7, 2000 · The effect of etoposide and camptothecin, two topoisomerase inhibitors directed against topoisomerases II and I, respectively, was evaluated on human peripheral … newchic englishWebThis compound also exerted a protective effect on tunicamycin-induced ER stress to a lesser extent but had no effect on campthothecin-, etoposide- or staurosporine-induced … new chic english websiteWebApr 29, 2024 · What is claimed is: 1. A method of inhibiting or partially inhibiting activity of one or more PIM (proviral integration site for Moloney murine leukemia virus) kinase(s) comprising contacting a PIM kinase with a compound of Formula (I) or Formula (II) or a pharmaceutically acceptable salt, solvate, hydrate, or N-oxide, prodrug, or isotopic … internet back up planWeb( S )- (+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a … internet backup solutions