Tagln smooth muscle

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August undefined, 2024

WebAug 23, 2024 · Airway smooth muscle (ASM) is a dynamic and complex tissue involved in regulation of bronchomotor tone, but the molecular events essential for the maintenance of ASM homeostasis are not well understood. Observational and genome-wide association studies in humans have linked airway function to the nutritional status of vitamin A and its … WebMay 18, 2015 · SMCs are distinguished from other cell types by expression of a unique repertoire of genes including Acta2, Tagln, and Myh11. These genes are coordinately …

KLF4-dependent phenotypic modulation of smooth muscle cells

WebNine genes were defined as hub genes: transgelin (TAGLN), alpha-smooth muscle actin (ACTA2), myosin heavy chain 11 (MYH11), caldesmon 1 (CALD1), myosin light chain kinase (MYLK), GTP-binding protein overexpressed in skeletal muscle (GEM), proline and arginine rich end leucine-rich repeat protein (PRELP), tropomyosin 2 (TPM2), and osteoglycin (OGN). WebMay 18, 2015 · Notably, in vivo studies from our laboratory showed that large numbers of ACTA2 −, myosin, heavy polypeptide 11, smooth muscle (MYH11) −, and transgelin (TAGLN) − cells within advanced ... fortran record number outside range

Anti-TAGLN/Transgelin antibody (ab10135) Abcam

WebSmooth muscle cells (SMC) line the walls of hollow organs in the body, including the intestines, uterus, bladder, stomach and arteries. It lacks the characteristic cross … WebMay 30, 2024 · Here, we find that mesoderm-derived pericytes (PCs) and smooth muscle cells (SMCs) originate from a clonal mesenchymal progenitor mesenchymoangioblast (MB). In clonogenic cultures, ... TAGLN, RGS5, PDGFRB, and ANGPT1 SMC and PC genes between mural cell populations generated from H1 hESCs was confirmed using qPCR (Figure S5 C). WebSep 19, 2024 · The effect of TAGLN was evaluated both in vitro and in vivo using transwell assay, immunofluorescence, western blot analysis and immunohistochemistry. Results: … fortran reference

Tagln smooth muscle

Identification of key pathways and genes influencing prognosis in ...

WebTransgelin is one of the earliest markers of differentiated smooth muscle cells and recent evidence suggests that transgelin acts as a tumor suppressor. Canine (100%), Bovine (100%). Backed by our 100% Guarantee. Test in a species/application not listed above to receive a full credit towards a future purchase. WebDec 16, 2015 · Within 1-2 weeks of myogenic differentiation, differentiating MSCs significantly expressed alpha smooth muscle actin (αSMA; ACTA2), transgelin (TAGLN), …

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WebSmooth muscle cells - Muscle contraction (mainly) Tissue cell type classification i Genes can have enriched specificity in different cell types in one or several tissues, or be … WebApr 6, 2024 · Smooth muscle cell (SMC) is a key component in neointimal hyperplasia in venous stenosis [6, 7]. ... SMCs were defined by Acta2 and Tagln (encoding SM22), while clusters 3 and 11 were defined as SPCs as they exclusively expressed Ly6a and Cd34 (Fig. S1C). Notably, compared to healthy vessels, Malat1 was downregulated in both AS groups …

WebPhenotype Plasticity of Vascular Smooth Muscle. Since the earliest ultrastructural studies of smooth muscle tissue, it has been apparent that SMCs exhibit a wide range of phenotypic variation. 13 – 17 In fact, this diversity was considered for many years to be evidence of not 1 but 2 different cell types in the tunica media of artery walls, 1 for contraction and … WebAug 1, 2024 · The actin-crosslinking protein TAGLN (transgelin, also known as SM22 or SM22α) is abundantly expressed in smooth muscle cells (SMCs) and is widely used as a …

WebWe have generated transgenic mouse lines expressing a tamoxifen-activated Cre recombinase, CreER (T2), under the control of the smooth muscle-specific SM22 promoter. Both a randomly integrated transgene [SM-CreER (T2) (tg)] and a transgene that has been "knocked in" into the endogenous SM22 locus [SM-CreER (T2) (ki)] were expressed in … WebJul 7, 2024 · TAGLN is an actin-binding protein family that comprises three isoforms with theorized roles in smooth muscle differentiation, tumour development, lymphocyte activation, and brain chemistry.

WebTransgelin is a protein that in humans is encoded by the TAGLN gene. The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling …

WebJul 7, 2024 · An actin cross-linking protein TAGLN (Transgelin, SM22 or SM22alpha) is abundantly expressed in smooth muscle cells (SMCs) and widely used as its canonical … dinner shows in pigeon forge 2021WebMar 27, 2024 · In Seurat v5, we introduce support for ‘niche’ analysis of spatial data, which demarcates regions of tissue (‘niches’), each of which is defined by a different composition of spatially adjacent cell types. Inspired by methods in Goltsev et al, Cell 2024 and He et al, NBT 2024, we consider the ‘local neighborhood’ for each cell ... dinner shows in pigeon forge areaWebMar 21, 2024 · TAGLN (Transgelin) is a Protein Coding gene. Diseases associated with TAGLN include Peyronie Disease and Aortic Dissection. Among its related pathways are … dinner shows in pigeon forge in jan 2020